Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.46 |
| ▸ | FLT4 | P35916 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20360313 | 1.00 | FLT1 (0.46) | FLT1FLT4KDRTSHRGAA | |
| SCHEMBL16974821 | 0.85 | TSHR (0.47) | TSHRGAAALDH1A1MAPTHPGD | |
| SCHEMBL1349424 | 0.81 | SMN1; SMN2 (0.59) | TSHRGAAALDH1A1MAPTHPGD | |
| SCHEMBL3312425 | 0.79 | FLT1 (0.44) | FLT1FLT4KDRTSHRALDH1A1 | |
| SCHEMBL3312420 | 0.79 | FLT1 (0.44) | FLT1FLT4KDRTSHRALDH1A1 | |
| SCHEMBL3312429 | 0.79 | FLT1 (0.44) | FLT1FLT4KDRTSHRALDH1A1 | |
| SCHEMBL16599458 | 0.78 | CXCL12 (0.50) | TSHRGAAALDH1A1HPGDPOLB | |
| SCHEMBL395189 | 0.76 | SMN1; SMN2 (0.63) | FLT1FLT4KDRTSHRGAA | |
| SCHEMBL11810626 | 0.76 | SMN1; SMN2 (0.52) | FLT1FLT4KDRTSHRALDH1A1 | |
| SCHEMBL1164132 | 0.76 | FLT1 (0.51) | FLT1FLT4KDRTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |