Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 7/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | TEK | Q02763 | 3/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702337 | 0.89 | DDR2 (0.64) | DDR2METKDRAURKATEK | |
| SCHEMBL30702345 | 0.86 | PDGFRA (0.58) | METKDRAURKATEKAURKB | |
| SCHEMBL30702360 | 0.86 | DDR2 (0.55) | DDR2METKDRAURKATEK | |
| SCHEMBL30702367 | 0.86 | DDR2 (0.53) | DDR2METKDRAURKATEK | |
| SCHEMBL29186588 | 0.86 | DDR2 (0.53) | DDR2METKDRAURKATEK | |
| SCHEMBL30702344 | 0.86 | DDR2 (0.53) | DDR2METKDRAURKATEK | |
| SCHEMBL30702339 | 0.86 | DDR2 (0.53) | DDR2METKDRAURKATEK | |
| SCHEMBL29186566 | 0.86 | DDR2 (0.53) | DDR2METKDRAURKATEK | |
| SCHEMBL29317823 | 0.84 | DDR2 (0.54) | DDR2PDGFRA | |
| SCHEMBL30702362 | 0.83 | DDR2 (0.50) | DDR2METKDRKDM4EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321036-A | phenyl-O-quinoline, quinazoline, thienopyridine, thienopyrimidine, pyrrolopyridine, pyrrolopyrimidine compounds having anticancer activity | 成都安泰康赛生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |