Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.70 |
| ▸ | FPR2 | P25090 | 5/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.51 |
| ▸ | DRD1 | P21728 | 5/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20412074 | 1.00 | KDM1A (0.70) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL20412131 | 0.99 | KDM1A (0.68) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL31673803 | 0.99 | KDM1A (0.68) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL20412119 | 0.98 | KDM1A (0.70) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL31673796 | 0.98 | KDM1A (0.70) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL20412091 | 0.97 | KDM1A (0.68) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL31673797 | 0.97 | KDM1A (0.68) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL20412090 | 0.90 | KDM1A (0.85) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL20412145 | 0.90 | KDM1A (0.63) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL20412110 | 0.89 | KDM1A (0.83) | KDM1AFPR2ADRA2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4260861-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | Seoul National University R & DB Foundation (KR) | 2023-10-18 | — | — | EP | claimed |
| EP-4260861-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | Seoul National University R & DB Foundation (KR) | 2023-10-18 | — | — | EP | disclosed |