⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15980884 | 1.00 | — | — | |
| SCHEMBL28814759 | 0.87 | KMT2A (0.45) | — | |
| SCHEMBL18231840 | 0.80 | — | — | |
| SCHEMBL60486 | 0.79 | — | — | |
| SCHEMBL60485 | 0.79 | — | — | |
| SCHEMBL11861934 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL11861938 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL4946068 | 0.75 | — | — | |
| SCHEMBL2162501 | 0.74 | — | — | |
| SCHEMBL2162505 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532645-A1 | 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS | Symrise AG (DE) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023232241-A1 | 5,5-DISUBSTITUED TETRAHYDROFURAN-2-ONE AS FRAGRANCE COMPOUNDS | SYMRISE AG (DE) | 2023-12-07 | — | — | WO | disclosed |