Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 3/20 | 0.34 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065774 | 1.00 | NPC1 (0.41) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15066190 | 1.00 | NPC1 (0.41) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL16669609 | 1.00 | NPC1 (0.41) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15069239 | 0.91 | NPC1 (0.39) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15069023 | 0.91 | NPC1 (0.39) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL21301285 | 0.91 | NPC1 (0.42) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15086329 | 0.91 | NPC1 (0.42) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15069221 | 0.91 | HTT (0.41) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL27261173 | 0.91 | MAOB (0.39) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15068754 | 0.90 | HTT (0.41) | NPC1ALDH1A1RAB9AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006287-A2 | ANTIVIRAL COMPOUNDS USEFUL AGAINST SARS-COV-2 | UNIVERSITY OF KANSAS (US) | 2024-01-04 | — | — | WO | claimed |
| WO-2024006287-A2 | ANTIVIRAL COMPOUNDS USEFUL AGAINST SARS-COV-2 | UNIVERSITY OF KANSAS (US) | 2024-01-04 | — | — | WO | disclosed |