Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30118007 | 0.90 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GDYRK1APDE10ANPC1 | |
| SCHEMBL30798766 | 0.89 | APOBEC3A (0.51) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A | |
| SCHEMBL1665644 | 0.88 | APOBEC3A (0.54) | APOBEC3AAPOBEC3GDYRK1APDE10ANPC1 | |
| SCHEMBL21076234 | 0.87 | DYRK1A (0.60) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A | |
| SCHEMBL30118009 | 0.86 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GDYRK1APDE10ANPC1 | |
| SCHEMBL1015835 | 0.85 | DYRK1A (0.62) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL25276515 | 0.83 | DYRK1A (0.60) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A | |
| SCHEMBL4154898 | 0.82 | MAPT (0.49) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A | |
| SCHEMBL5060955 | 0.82 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A | |
| SCHEMBL5946565 | 0.82 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GDYRK1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120442-A | Tricyclic compounds useful for treating cancer, autoimmune disorders, and inflammatory disorders | 薛定谔公司 | 2023-11-24 | — | — | CN | disclosed |