Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 5/20 | 0.35 |
| ▸ | FNTB | P49356 | 5/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412163 | 1.00 | ACE (0.47) | ACEPDCD1LG2CD274KDM4EMAPT | |
| SCHEMBL30288040 | 0.95 | ACE (0.51) | ACEPDCD1LG2CD274KDM4EMAPT | |
| SCHEMBL30288047 | 0.91 | ACE (0.48) | ACEPDCD1LG2CD274KDM4EMAPT | |
| SCHEMBL29461589 | 0.91 | ACE (0.56) | ACEPDCD1LG2CD274KDM4EMAPT | |
| SCHEMBL30252928 | 0.87 | ACE (0.49) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30010271 | 0.86 | ACE (0.54) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30011113 | 0.86 | ACE (0.54) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30011222 | 0.86 | ACE (0.54) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30010300 | 0.86 | ACE (0.54) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30011355 | 0.86 | ACE (0.48) | ACEPDCD1LG2CD274KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247446-B | Restructured short peptide and application thereof | 江苏省人民医院（南京医科大学第一附属医院） | 2024-05-14 | — | — | CN | disclosed |
| CN-117247446-A | Restructured short peptide and application thereof | 江苏省人民医院（南京医科大学第一附属医院） | 2023-12-19 | — | — | CN | disclosed |