Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.70 |
| ▸ | HTR2A | P28223 | 7/20 | 0.70 |
| ▸ | HTR2B | P41595 | 7/20 | 0.70 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033783 | 1.00 | HTR2C (0.70) | HTR2CHTR2AHTR2BSLC9A1DRD2 | |
| SCHEMBL27033837 | 0.84 | HTR2C (0.72) | HTR2CHTR2AHTR2BSLC9A1DRD2 | |
| SCHEMBL30711631 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BSLC6A3SLC6A4 | |
| SCHEMBL22335135 | 0.82 | HTR2C (0.70) | HTR2CHTR2AHTR2BSLC9A1DRD2 | |
| SCHEMBL27033673 | 0.82 | HTR2C (1.00) | HTR2CHTR2AHTR2BSLC6A3SLC6A4 | |
| SCHEMBL24737408 | 0.80 | HTR2A (0.62) | HTR2CHTR2AHTR2BSLC9A1 | |
| SCHEMBL24738380 | 0.79 | HTR2C (0.65) | HTR2CHTR2AHTR2BSLC9A1DRD2 | |
| SCHEMBL7959436 | 0.79 | HTR2C (0.68) | HTR2CHTR2AHTR2BSLC6A3SLC6A4 | |
| SCHEMBL14602807 | 0.79 | HTR2C (0.68) | HTR2CHTR2AHTR2BSLC6A3SLC6A4 | |
| SCHEMBL7959439 | 0.79 | HTR2C (0.68) | HTR2CHTR2AHTR2BSLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |