Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CKS1B | P61024 | 3/20 | 0.49 |
| ▸ | SKP1 | P63208 | 3/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456253 | 1.00 | CNR1 (0.66) | CNR1ALOX15ALDH1A1HPGDHSD17B10 | |
| SCHEMBL476267 | 0.85 | CNR1 (0.62) | CNR1ALDH1A1CKS1BSKP1SKP2 | |
| SCHEMBL2834588 | 0.85 | CNR1 (0.62) | CNR1ALDH1A1CKS1BSKP1SKP2 | |
| SCHEMBL2704945 | 0.84 | CNR1 (0.67) | CNR1LMNAL3MBTL1KDM4EGAA | |
| SCHEMBL4456962 | 0.84 | CNR1 (0.57) | CNR1ALOX15ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4465958 | 0.84 | CNR1 (0.69) | CNR1 | |
| SCHEMBL2830367 | 0.81 | CNR1 (0.61) | CNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2837164 | 0.81 | CNR1 (0.57) | CNR1CKS1BSKP1SKP2L3MBTL1 | |
| SCHEMBL30712635 | 0.81 | CNR1 (0.61) | CNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4451106 | 0.80 | CNR1 (1.00) | CNR1ALDH1A1LMNAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024009283-A1 | AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |