Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 4/20 | 0.49 |
| ▸ | NPY4R | P50391 | 7/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.47 |
| ▸ | NPY1R | P25929 | 5/20 | 0.47 |
| ▸ | NPY2R | P49146 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572744 | 1.00 | GNPAT (0.50) | GNPATMC4RNPY4RNPY5RNPY1R | |
| SCHEMBL30712847 | 1.00 | GNPAT (0.50) | GNPATMC4RNPY4RNPY5RNPY1R | |
| SCHEMBL30712846 | 1.00 | GNPAT (0.50) | GNPATMC4RNPY4RNPY5RNPY1R | |
| SCHEMBL30712856 | 0.97 | GNPAT (0.49) | GNPATMC4RNPY4RNPY5RNPY1R | |
| SCHEMBL19656447 | 0.94 | NPY4R (0.54) | MC4RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30712842 | 0.93 | GNPAT (0.52) | GNPATMC4RMMEACECPA1 | |
| SCHEMBL30029024 | 0.92 | GNPAT (0.56) | GNPATMC4RNPY4RNPY5RNPY1R | |
| SCHEMBL29968334 | 0.90 | ALB (0.53) | GNPATNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL6551485 | 0.90 | MC4R (0.57) | MC4RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL6552855 | 0.90 | MC4R (0.57) | MC4RNPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002438-A1 | MELANOCORTIN LIGANDS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2024-01-04 | — | — | US | claimed |
| US-20240002438-A1 | MELANOCORTIN LIGANDS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2024-01-04 | — | — | US | disclosed |