Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171657 | 1.00 | MAPT (0.53) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30713111 | 0.90 | MAPT (0.56) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27171644 | 0.90 | MAPT (0.56) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30713157 | 0.86 | MAPT (0.58) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27171646 | 0.86 | MAPT (0.58) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21605010 | 0.82 | MAPT (0.59) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27171661 | 0.82 | POLB (0.62) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30097896 | 0.82 | POLB (0.62) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30861257 | 0.81 | POLB (0.60) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27171662 | 0.81 | POLB (0.60) | MAPTPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425480-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | LG CHEM, LTD. (KR) | 2024-12-26 | — | — | US | disclosed |
| CN-117500804-A | Novel urea derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117396468-A | Novel pyridine derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-01-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425480-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | RET, MST1R, ROS1 | MAPT 4286/4885POLB 4572/4885SMN1; SMN2 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.