SCHEMBL30713343

SCHEMBL30713343

C[C@H](NC(=O)N1CCn2c(C#N)c(-c3cccc(F)c3)c(C(N)=O)c2C1)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CSNK1E P49674 20/20 1.00
▸ CSNK1D P48730 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14841244 1.00 CSNK1E (1.00) CSNK1ECSNK1D
SCHEMBL14841450 0.87 CSNK1E (1.00) CSNK1E
SCHEMBL30713392 0.87 CSNK1E (1.00) CSNK1E
SCHEMBL30713377 0.86 CSNK1E (0.76) CSNK1ECSNK1D
SCHEMBL31201 0.86 CSNK1E (0.76) CSNK1ECSNK1D
SCHEMBL30713341 0.86 CSNK1E (0.77) CSNK1ECSNK1D
SCHEMBL14841418 0.86 CSNK1E (0.77) CSNK1ECSNK1D
SCHEMBL14841545 0.83 CSNK1E (0.70) CSNK1E
SCHEMBL14841021 0.82 CSNK1E (1.00) CSNK1ECSNK1D
SCHEMBL30713311 0.82 CSNK1E (1.00) CSNK1ECSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000821-A1 CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER UNIV JOHNS HOPKINS (US) 2024-01-04 — — US disclosed
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