SCHEMBL30713359

SCHEMBL30713359

NC(=O)c1c(-c2cccc(F)c2)c(Cl)n2c1CN(C(=O)N[C@H]1CC[C@H](O)CC1)CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSNK1E P49674 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31219 1.00 CSNK1E (1.00) CSNK1E
SCHEMBL15890845 1.00 CSNK1E (1.00) CSNK1E
SCHEMBL30713315 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL14841557 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL30713314 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL14841656 0.90 CSNK1E (0.87) CSNK1E
SCHEMBL30713339 0.89 CSNK1E (1.00) CSNK1E
SCHEMBL14841165 0.89 CSNK1E (1.00) CSNK1E
SCHEMBL30713393 0.88 CSNK1E (1.00) CSNK1E
SCHEMBL30713363 0.88 CSNK1E (1.00) CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000821-A1 CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER UNIV JOHNS HOPKINS (US) 2024-01-04 — — US disclosed
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