SCHEMBL30713367

SCHEMBL30713367

CC(C)(CO)CNC(=O)N1CCn2c(Cl)c(-c3cccc(F)c3)c(C(N)=O)c2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31265 1.00 CSNK1E (1.00) CSNK1E
SCHEMBL30713340 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL14841745 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL30713370 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL14841421 0.90 CSNK1E (1.00) CSNK1E
SCHEMBL30713321 0.86 CSNK1E (1.00) CSNK1E
SCHEMBL30713362 0.85 CSNK1E (1.00) CSNK1E
SCHEMBL14841573 0.85 CSNK1E (1.00) CSNK1E
SCHEMBL14849298 0.85 CSNK1E (0.73) CSNK1E
SCHEMBL30713381 0.83 CSNK1E (1.00) CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000821-A1 CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER UNIV JOHNS HOPKINS (US) 2024-01-04 US disclosed