SCHEMBL30713368

SCHEMBL30713368

NC(=O)c1c(-c2ccccc2)c(Cl)n2c1CN(C(=O)NCC1CC1)CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSNK1E P49674 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14841492 0.84 CSNK1E (1.00) CSNK1E
SCHEMBL14841550 0.84 CSNK1E (1.00) CSNK1E
SCHEMBL14841539 0.84 CSNK1E (1.00) CSNK1E
SCHEMBL14841286 0.83 CSNK1E (1.00) CSNK1E
SCHEMBL30713379 0.83 CSNK1E (1.00) CSNK1E
SCHEMBL14841680 0.82 CSNK1E (1.00) CSNK1E
SCHEMBL14841725 0.82 CSNK1E (1.00) CSNK1E
SCHEMBL13964190 0.82 CSNK1E (0.70) CSNK1E
SCHEMBL30713345 0.82 CSNK1E (1.00) CSNK1E
SCHEMBL14841570 0.81 CSNK1E (0.72) CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000821-A1 CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER UNIV JOHNS HOPKINS (US) 2024-01-04 — — US disclosed
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