Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 5/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 6/20 | 0.37 |
| ▸ | PDE4A | P27815 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26869335 | 1.00 | SMO (0.39) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL30714664 | 0.94 | SMO (0.41) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL26871154 | 0.90 | SMO (0.37) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL26869323 | 0.90 | SMO (0.39) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL26868364 | 0.88 | SMO (0.38) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL26868963 | 0.86 | SMO (0.40) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL30714591 | 0.85 | PARP10 (0.41) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL26869163 | 0.84 | SMO (0.39) | SMOMAPK14CYP2C9KCNH2PDE5A | |
| SCHEMBL26868978 | 0.82 | GUCY1B2 (0.43) | SMOMAPK14CYP2C9KCNH2 | |
| SCHEMBL26696087 | 0.82 | SMO (0.37) | SMOMAPK14CYP2C9KCNH2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968362-A | Indazole derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2025-05-09 | — | — | CN | disclosed |
| EP-4499624-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |