Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 5/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624068 | 0.85 | POLB (0.54) | POLBSMYD3TEAD1TSHRKDM4E | |
| SCHEMBL308515 | 0.85 | — | — | |
| SCHEMBL18073056 | 0.82 | POLB (0.48) | POLBSMYD3TEAD1TSHRBTK | |
| SCHEMBL18073055 | 0.82 | POLB (0.48) | POLBSMYD3TEAD1TSHRBTK | |
| SCHEMBL20839730 | 0.82 | POLB (0.48) | POLBSMYD3TEAD1TSHRBTK | |
| SCHEMBL22660898 | 0.82 | POLB (0.47) | POLBSMYD3TEAD1BTKHTT | |
| SCHEMBL18972634 | 0.80 | POLB (0.45) | POLBSMYD3TEAD1HTT | |
| SCHEMBL19409139 | 0.80 | POLB (0.45) | POLBSMYD3TEAD1HTT | |
| SCHEMBL18972633 | 0.80 | POLB (0.45) | POLBSMYD3TEAD1HTT | |
| SCHEMBL22432866 | 0.79 | SMYD3 (0.41) | POLBSMYD3TEAD1BTKHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |