Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 16/20 | 0.59 |
| ▸ | CDK12 | Q9NYV4 | 16/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.59 |
| ▸ | CDK9 | P50750 | 15/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.59 |
| ▸ | CDK2 | P24941 | 14/20 | 0.59 |
| ▸ | CDK7 | P50613 | 12/20 | 0.59 |
| ▸ | CCNH | P51946 | 12/20 | 0.59 |
| ▸ | MNAT1 | P51948 | 11/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696965 | 1.00 | CCNK (0.59) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL26696963 | 1.00 | CCNK (0.59) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL26696858 | 0.84 | CCNK (0.63) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL30716188 | 0.84 | CCNK (0.63) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL28817296 | 0.79 | CCNK (0.78) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL28817298 | 0.79 | CCNK (0.78) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL31448134 | 0.76 | CCNK (0.46) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29498451 | 0.75 | CDK7 (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22115126 | 0.75 | CDK7 (1.00) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076294 | 0.74 | CCNK (0.79) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |