Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.73 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.63 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622030 | 1.00 | CRBN (0.73) | CRBNDDB1IKZF2CSNK1A1 | |
| SCHEMBL20233779 | 0.90 | CRBN (0.73) | CRBNDDB1 | |
| SCHEMBL29884126 | 0.90 | CRBN (0.73) | CRBNDDB1 | |
| SCHEMBL30496981 | 0.90 | CRBN (0.73) | CRBNDDB1 | |
| SCHEMBL31158668 | 0.86 | CRBN (0.59) | CRBNDDB1IKZF2CSNK1A1 | |
| SCHEMBL29482963 | 0.86 | CRBN (0.75) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20765391 | 0.86 | CRBN (0.75) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL23298653 | 0.85 | CRBN (0.73) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL22703752 | 0.85 | CRBN (0.73) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL22703743 | 0.85 | CRBN (0.73) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459451-A | Phenyl urea compound and preparation method and application thereof | 四川大学 | 2024-08-09 | — | — | CN | claimed |
| EP-4683934-A1 | SYSTEM | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024194645-A1 | SYSTEM | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2024-09-26 | — | — | WO | disclosed |
| WO-2024192064-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A/ PROTEOVANT THERAPEUTICS, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| CN-118459451-A | Phenyl urea compound and preparation method and application thereof | 四川大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-117402164-A | Aryl-substituted nitrogen-containing heterocyclic compounds | 杭州德睿智药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |