SCHEMBL30717524

SCHEMBL30717524

CC(C)C(C)(C)C(=O)N1CCc2nc(N3C4CCC3CNC4)sc2C1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OGA O60502 1/20 0.37
GRAMD1A Q96CP6 1/20 0.35
GRM5 P41594 16/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717360 0.89 HDAC6 (0.38) OGAGRM5NPC1RAB9A
SCHEMBL30717334 0.86 OGA (0.35) OGAGRAMD1AGRM5NPC1RAB9A
SCHEMBL30717371 0.86 PDK2 (0.35) OGAGRM5NPC1RAB9A
SCHEMBL30717354 0.86 NPC1 (0.36) OGAGRAMD1AGRM5NPC1RAB9A
SCHEMBL30717413 0.85 OGA (0.37) OGAGRM5NPC1RAB9A
SCHEMBL30717557 0.85 GRM5 (0.35) OGAGRM5NPC1RAB9A
SCHEMBL30717513 0.84 GRM5 (0.35) OGAGRM5NPC1RAB9A
SCHEMBL30717518 0.83 OGA (0.36) OGAGRM5NPC1RAB9A
SCHEMBL30717433 0.83 OGA (0.36) OGAGRM5NPC1RAB9A
SCHEMBL30717428 0.83 OGA (0.36) OGAGRM5NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP claimed
WO-2024038128-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS MIRONID LIMITED (GB) 2024-02-22 WO claimed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
WO-2024038128-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS MIRONID LIMITED (GB) 2024-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B OGA 2031/4885GRAMD1A 4161/4885GRM5 2029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.