Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931212 | 1.00 | MAOB (0.51) | MAOBTSHRMAOALMNAMAPT | |
| SCHEMBL7931200 | 0.93 | MAOB (0.45) | MAOBTSHRMAOALMNAMAPT | |
| SCHEMBL31366954 | 0.89 | MAOB (0.51) | MAOBMAOALMNANPC1TP53 | |
| SCHEMBL791137 | 0.89 | MAOB (0.51) | MAOBMAOALMNANPC1TP53 | |
| SCHEMBL20291465 | 0.86 | TSHR (0.44) | MAOBTSHRMAOALMNAMAPT | |
| SCHEMBL7481006 | 0.84 | MAOB (0.51) | MAOBTSHRMAOALMNAMAPT | |
| SCHEMBL38661426 | 0.81 | TSHR (0.46) | MAOBTSHRMAOALMNAMAPT | |
| SCHEMBL31180358 | 0.80 | PRKCI (0.47) | MAPTNPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL2937683 | 0.80 | PRKCI (0.47) | MAPTNPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL7928453 | 0.78 | CTNNB1 (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330967-B | MET transcription inhibitor and preparation method and application thereof | 中国药科大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119330967-A | MET transcription inhibitor and preparation method and application thereof | 中国药科大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |