Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913751 | 0.88 | F2 (0.52) | F2MMP7ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29913704 | 0.82 | F2 (0.52) | F2MMP7ALDH1A1SMN1; SMN2BACE1 | |
| SCHEMBL30718537 | 0.82 | F2 (0.52) | F2MMP7ALDH1A1SMN1; SMN2BACE1 | |
| SCHEMBL30718534 | 0.75 | F2 (0.49) | F2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30718508 | 0.74 | F2 (0.48) | F2ALDH1A1LMNA | |
| SCHEMBL29913816 | 0.74 | F2 (0.46) | F2ALDH1A1 | |
| SCHEMBL30718544 | 0.73 | F2 (0.47) | F2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4373557 | 0.73 | F2 (0.51) | F2ALDH1A1 | |
| SCHEMBL6066041 | 0.73 | F2 (0.51) | F2ALDH1A1 | |
| SCHEMBL6528253 | 0.72 | BACE1 (0.41) | MMP7BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304129-A | Azaalkanone derivative or pharmaceutically acceptable salt thereof, preparation method and application thereof, and pharmaceutical composition | 中国医学科学院医药生物技术研究所 | 2023-12-29 | — | — | CN | disclosed |