SCHEMBL30718661

SCHEMBL30718661

O=C1CCC(N2Cc3ccc(O[C@H]4CCNC4)cc3C2=O)C(=O)N1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27152826 1.00 CRBN (0.64) CRBN
Hydrochloric Acid SCHEMBL30718890 0.99 CRBN (0.63) CRBN
Hydrochloric Acid SCHEMBL27139207 0.99 CRBN (0.63) CRBN
Hydrochloric Acid SCHEMBL27139208 0.99 CRBN (0.63) CRBN
SCHEMBL27208467 0.94 CRBN (0.66) CRBN
SCHEMBL30822397 0.94 CRBN (0.66) CRBN
SCHEMBL22291530 0.93 CRBN (0.67) CRBN
SCHEMBL29369888 0.93 CRBN (0.67) CRBN
SCHEMBL23350211 0.92 CRBN (0.63) CRBN
SCHEMBL20231670 0.92 CRBN (0.63) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547658-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF Bristol-Myers Squibb Company (US) 2025-05-07 — — EP disclosed
CN-119325469-A WEE1 degrading compounds and uses thereof 百时美施贵宝公司 2025-01-17 — — CN disclosed
WO-2024006881-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2024-01-04 — — WO disclosed
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