Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 9/20 | 0.58 |
| ▸ | CCND1 | P24385 | 9/20 | 0.58 |
| ▸ | CCND2 | P30279 | 7/20 | 0.58 |
| ▸ | CCND3 | P30281 | 7/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23141961 | 1.00 | CDK4 (0.58) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL23141962 | 1.00 | CDK4 (0.58) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL30718886 | 0.88 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL23141847 | 0.88 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL23141812 | 0.88 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL23141809 | 0.88 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL23141849 | 0.88 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL6801181 | 0.88 | CDK4 (0.44) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL29991137 | 0.86 | CDK4 (0.54) | CDK4CCND1CCND2CCND3CCNE1 | |
| SCHEMBL5264817 | 0.86 | CDK4 (0.54) | CDK4CCND1CCND2CCND3CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469719-B | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2024-01-23 | — | — | CN | disclosed |