Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21630625 | 1.00 | ELANE (0.48) | ELANEGSK3BGRM5KMT2AMEN1 | |
| SCHEMBL14725968 | 0.85 | ELANE (0.50) | ELANEKMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28560572 | 0.80 | SMN1; SMN2 (0.46) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL29977154 | 0.80 | SMN1; SMN2 (0.46) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL28554740 | 0.79 | KMT2A (0.48) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL28546956 | 0.79 | SMN1; SMN2 (0.40) | KMT2AMEN1GAACYP1A2SMN1; SMN2 | |
| SCHEMBL23112463 | 0.78 | NOTUM (0.49) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL29977559 | 0.78 | NOTUM (0.49) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL29977403 | 0.77 | SMN1; SMN2 (0.43) | ELANEKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL28556855 | 0.77 | SMN1; SMN2 (0.43) | ELANEKMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166153-B | Fused pyrazine derivatives as A2A/A2B inhibitors | 因赛特公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-117304191-A | Fused pyrazine derivatives as A2A/A2B inhibitors | 因赛特公司 | 2023-12-29 | — | — | CN | disclosed |