Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719408 | 0.85 | MAPKAPK2 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL30719396 | 0.82 | SYK (0.39) | HRH4CHIAUSP2ALDH1A1CYP1A2 | |
| SCHEMBL21552883 | 0.78 | SYK (0.37) | HRH4USP2ALDH1A1CYP1A2CASP1 | |
| SCHEMBL12892361 | 0.78 | KDM4E (0.55) | USP2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL30719413 | 0.77 | GRIA1 (0.41) | SYK | |
| SCHEMBL23258205 | 0.76 | SYK (0.39) | HRH4USP2ALDH1A1CYP1A2CASP1 | |
| SCHEMBL21553146 | 0.76 | SYK (0.40) | CHIASYKKDM4ERAB9AL3MBTL1 | |
| SCHEMBL21564622 | 0.72 | MTOR (0.40) | HRH4CHIAALDH1A1CYP3A4SYK | |
| SCHEMBL30719390 | 0.69 | KDM4C (0.40) | CYP1A2CYP3A4CLK4KDM4E | |
| SCHEMBL30719383 | 0.68 | MAPKAPK2 (0.39) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |