Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 17/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124591 | 0.92 | ADORA2A (0.62) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20417122 | 0.90 | ADORA2A (0.79) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20421947 | 0.89 | ADORA2A (0.60) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30401948 | 0.88 | ADORA2A (0.66) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30401237 | 0.88 | ADORA2A (0.66) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401327 | 0.88 | ADORA2A (0.66) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20400366 | 0.88 | ADORA2A (0.66) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30401095 | 0.86 | ADORA2A (0.65) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20416592 | 0.86 | ADORA2A (0.65) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30401971 | 0.85 | ADORA2A (0.65) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310082-A2 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | Arcus Biosciences, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |