Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416578 | 1.00 | ADORA2A (0.48) | ADORA2AADORA2BADORA1KLKB1 | |
| SCHEMBL20400520 | 0.92 | ADORA2A (0.49) | ADORA2AADORA2BADORA1KLKB1 | |
| SCHEMBL20436455 | 0.91 | ADORA2A (0.50) | ADORA2AADORA2BADORA1KLKB1 | |
| SCHEMBL20416872 | 0.90 | ADORA2A (0.49) | ADORA2AADORA2BADORA1KLKB1 | |
| SCHEMBL20416792 | 0.87 | ADORA2A (0.47) | ADORA2AADORA2BADORA1KLKB1 | |
| SCHEMBL20400598 | 0.86 | ADORA2A (0.52) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20400874 | 0.86 | ADORA2A (0.52) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30402211 | 0.85 | ADORA2A (0.49) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20400534 | 0.85 | ADORA2A (0.49) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20400518 | 0.85 | ADORA2A (0.60) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310082-A2 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | Arcus Biosciences, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |