SCHEMBL30722121

SCHEMBL30722121

CC(C)(C)OC(=O)NC1(c2ccc(C(=O)CBr)c(F)c2)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 8/20 0.36
AKT1 P31749 3/20 0.35
RORC P51449 1/20 0.35
DRD2 P14416 3/20 0.34
USP30 Q70CQ3 1/20 0.34
AKT2 P31751 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
P2RX7 Q99572 1/20 0.33
AAK1 Q2M2I8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26992065 1.00 PDE2A (0.36) PDE2AAKT1RORCDRD2USP30
SCHEMBL1783824 0.82 AAK1 (0.38) PDE2AAKT1RORCDRD2AKT2
SCHEMBL30722172 0.82 AAK1 (0.38) PDE2AAKT1RORCDRD2AKT2
SCHEMBL26987193 0.82 PDE2A (0.36) PDE2ADRD2DPP8DPP9
SCHEMBL26992064 0.81 PDE2A (0.36) PDE2AAKT1RORCDRD2DPP8
SCHEMBL30722109 0.81 PDE2A (0.36) PDE2AAKT1RORCDRD2DPP8
SCHEMBL4549963 0.76 AKT1 (0.40) AKT1DRD2AKT2
SCHEMBL18769489 0.75 AKT1 (0.42) PDE2AAKT1RORCDRD2AKT2
SCHEMBL30145611 0.75 AKT1 (0.42) PDE2AAKT1RORCDRD2AKT2
SCHEMBL16897598 0.74 PDE2A (0.40) PDE2AAKT1RORCDRD2DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-09-02 US disclosed
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-24 US disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 PDE2A 4318/4885AKT1 1451/4885RORC 2270/4885
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 PDE2A 4318/4885AKT1 1451/4885RORC 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.