SCHEMBL30723949

SCHEMBL30723949

COC(OC)C1CCN(c2ccc(C3=C(c4ccc(F)cc4)CCCc4c3ccc3c4c(F)nn3C3CCCCO3)cc2)CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.33
ESR1 P03372 3/20 0.31
ESR2 Q92731 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30724013 0.95 ESR1 (0.30) ESR1ESR2
SCHEMBL30724076 0.93 ESR1 (0.35) ESR1
SCHEMBL30723843 0.92
SCHEMBL30724025 0.92 ESR1 (0.32) ESR1
SCHEMBL30723965 0.91
SCHEMBL30723763 0.91 ATR (0.30) ESR1
SCHEMBL30723839 0.90
SCHEMBL30723953 0.90
SCHEMBL30723938 0.90
SCHEMBL30723907 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024006776-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF RELAY THERAPEUTICS, INC. (US) 2024-01-04 WO disclosed