Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634070 | 1.00 | CYP4F2 (0.37) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL30861031 | 0.85 | GAA (0.44) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL27227964 | 0.85 | GAA (0.44) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL15265438 | 0.85 | CYP4F2 (0.37) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL15266811 | 0.80 | CYP4F2 (0.34) | CYP4F2CYP4A11RETALDH1A1POLB | |
| SCHEMBL25281611 | 0.79 | CYP4F2 (0.33) | CYP4F2CYP4A11RETALDH1A1POLB | |
| SCHEMBL19485522 | 0.79 | MAP3K5 (0.39) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL29879089 | 0.79 | MAP3K5 (0.39) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL24268660 | 0.79 | MAP3K5 (0.39) | CYP4F2CYP4A11PDE10ARETALDH1A1 | |
| SCHEMBL15278583 | 0.78 | CREBBP (0.35) | CYP4F2CYP4A11MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |