Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.33 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724675 | 0.83 | HDAC8 (0.47) | KDM4EGAAMAPK1HDAC8HDAC6 | |
| SCHEMBL30724659 | 0.81 | KDM4E (0.48) | KDM4EGAAMAPK1HDAC8HDAC6 | |
| SCHEMBL15594429 | 0.79 | KDM4E (0.53) | KDM4EGAAMAPK1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL27142541 | 0.77 | KDM4E (0.52) | KDM4EGAAMAPK1HDAC8HDAC6 | |
| SCHEMBL30724695 | 0.76 | HDAC8 (0.50) | KDM4EGAAMAPK1HDAC8HDAC6 | |
| SCHEMBL30724690 | 0.76 | HDAC8 (0.47) | KDM4EGAAMAPK1HDAC8HDAC6 | |
| SCHEMBL246119 | 0.71 | KDM4E (0.78) | KDM4EGAAMAPK1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1936751 | 0.69 | KDM4E (0.75) | KDM4EGAAMAPK1ALDH1A1HTT | |
| SCHEMBL12162873 | 0.67 | KDM4E (0.87) | KDM4EGAAMAPK1HDAC6ALDH1A1 | |
| SCHEMBL6190784 | 0.67 | KDM4E (0.95) | KDM4EGAAMAPK1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |