Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 5/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL11156967 | 0.84 | GLA (0.49) | GLAMAPTCYP1A2KDM4ES1PR1 | |
| SCHEMBL767862 | 0.83 | TSHR (0.65) | GLAMAPTS1PR1TSHRMEN1 | |
| SCHEMBL6299214 | 0.83 | MAPT (0.58) | GLAMAPTTSHRMEN1ALDH1A1 | |
| SCHEMBL767863 | 0.83 | TSHR (0.65) | GLAMAPTS1PR1TSHRMEN1 | |
| SCHEMBL4688972 | 0.82 | TSHR (0.47) | GLAMAPTCYP1A2KDM4ES1PR1 | |
| SCHEMBL4684050 | 0.82 | TSHR (0.47) | GLAMAPTCYP1A2KDM4ES1PR1 | |
| SCHEMBL11464779 | 0.81 | TSHR (0.67) | MAPTCYP1A2KDM4ETSHRMAPK1 | |
| SCHEMBL27986481 | 0.81 | S1PR1 (0.53) | GLAMAPTCYP1A2KDM4ES1PR1 | |
| SCHEMBL27986479 | 0.81 | S1PR1 (0.61) | GLAMAPTCYP1A2KDM4ES1PR1 | |
| SCHEMBL4684045 | 0.80 | S1PR1 (0.46) | GLAMAPTCYP1A2KDM4ES1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118223194-A | Soft and durable nonwoven web | 金伯利-克拉克环球有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4384575-A1 | LASER TRANSPARENT COMPOSITION AND MOLDED ARTICLES MADE THEREFROM | Celanese International Corporation (US) | 2024-06-19 | — | — | EP | disclosed |
| US-11993707-B2 | Polymer composite containing recycled carbon fibers | CELANESE SALES GERMANY GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| CN-118103449-A | Laser transparent composition and molded article made therefrom | 国际人造丝公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118019791-A | Thermoplastic polymer composition with enhanced tracking resistance and polymer articles made therefrom | 国际人造丝公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20240133091-A1 | CD Extensible Nonwoven Composite | KIMBERLY-CLARK WORLDWIDE, INC. | 2024-04-25 | — | — | US | disclosed |
| EP-4352150-A1 | THERMOPLASTIC POLYMER COMPOSITION WITH INCREASED ELECTRICAL TRACKING RESISTANCE AND POLYMER ARTICLES MADE THEREFROM | Celanese International Corporation (US) | 2024-04-17 | — | — | EP | disclosed |
| US-20240101812-A1 | Laser Weldable Polyester Composition | CELANESE INT CORP (US) | 2024-03-28 | — | — | US | disclosed |
| US-20240084081-A1 | Polyester Polymer Compositions | CELANESE SALES GERMANY GMBH (DE) | 2024-03-14 | — | — | US | disclosed |
| US-11851792-B2 | CD extensible nonwoven composite | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| CN-101755000-A | stabilized thermoplastic copolyesters | TICONA LLC | 2010-06-23 | — | — | CN | disclosed |
| EP-2170987-A1 | STABILIZED THERMOPLASTIC COPOLYESTERS | Ticona LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009012003-A1 | STABILIZED THERMOPLASTIC COPOLYESTERS | TICONA LLC (US) | 2009-01-22 | — | — | WO | disclosed |
| US-7053114-B2 | Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives | SUGEN, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-6797725-B2 | SUCH AS 4-METHYL-5-(2-OXO-1,2-DIHYDROINDOL-3-YLILDENEMETHYL)-1H-PYRROLE-2-CARBOXYLIC ACID FOR PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED CELLULAR DISORDERS; ANTICANCER AGENTS | SUGEN, INC. | 2004-09-28 | — | — | US | disclosed |
| US-20040186161-A1 | Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives | SUGEN, INC. | 2004-09-23 | — | — | US | disclosed |
| US-20030100555-A1 | Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives | SUGEN. INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2002081466-A1 | PRODRUGS OF 3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES | SUGEN, INC. (US) | 2002-10-17 | — | — | WO | disclosed |
| EP-0601725-B1 | Adhesion promoter compositions | LOCTITE CORP (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5164436-A | Mold release agents for clear thermoplastic resins | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186161-A1 | Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives | PLK2, CDK2, PDPK1 | GLA 2658/4885MAPT 3067/4885CYP1A2 1686/4885 |
| US-20030100555-A1 | Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives | PLK2, CDK2, PDPK1 | GLA 2658/4885MAPT 3067/4885CYP1A2 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.