Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033294 | 1.00 | MAOB (0.33) | MAOBESR1ESR2INPPL1BACE1 | |
| SCHEMBL27033332 | 0.93 | MAOB (0.35) | MAOBESR1ESR2INPPL1BACE1 | |
| SCHEMBL25520053 | 0.84 | ESR1 (0.43) | MAOBESR1ESR2BACE1MAPT | |
| SCHEMBL27033314 | 0.83 | MAPT (0.34) | MAOBESR1ESR2BACE1MAPT | |
| SCHEMBL31538921 | 0.83 | MAPT (0.34) | MAOBESR1ESR2BACE1MAPT | |
| SCHEMBL25522215 | 0.81 | ESR1 (0.40) | MAOBESR1ESR2BACE1MAPT | |
| SCHEMBL27033331 | 0.76 | MAPT (0.36) | MAOBESR1ESR2BACE1MAPT | |
| SCHEMBL27033287 | 0.74 | MAP4K4 (0.41) | MAP4K4 | |
| SCHEMBL27033328 | 0.73 | NPC1 (0.41) | INPPL1MIF | |
| SCHEMBL25521798 | 0.72 | MAOB (0.41) | MAOBESR1ESR2BACE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894865-A | Aryl hydrocarbon receptor agonist prodrugs and methods of use thereof | 元启(苏州)生物制药有限公司 | 2025-04-25 | — | — | CN | claimed |
| EP-4558478-A1 | ARYL HYDROCARBON RECEPTOR AGONIST PRODRUGS AND METHODS OF USE THEREOF | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-05-28 | — | — | EP | disclosed |
| CN-119894865-A | Aryl hydrocarbon receptor agonist prodrugs and methods of use thereof | 元启(苏州)生物制药有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024020170-A1 | ARYL HYDROCARBON RECEPTOR AGONIST PRODRUGS AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-01-25 | — | — | WO | disclosed |