Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 19/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.41 |
| ▸ | CCND1 | P24385 | 12/20 | 0.41 |
| ▸ | CDK4 | P11802 | 9/20 | 0.41 |
| ▸ | CDK1 | P06493 | 5/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 9/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.39 |
| ▸ | CDK9 | P50750 | 4/20 | 0.39 |
| ▸ | CCND3 | P30281 | 4/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | RB1 | P06400 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033500 | 1.00 | CDK2 (0.41) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL27033464 | 0.83 | CDK2 (0.49) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30726203 | 0.83 | CDK2 (0.49) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30726225 | 0.79 | CDK2 (0.51) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL27033439 | 0.79 | CDK2 (0.51) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30726205 | 0.77 | CDK2 (0.47) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL27033307 | 0.77 | CDK2 (0.47) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30804793 | 0.74 | CDK2 (0.58) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL27061752 | 0.74 | CDK2 (0.58) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30726228 | 0.72 | CDK2 (0.45) | CDK2CCNE1CCND1CDK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558493-A1 | QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020380-A1 | QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |