Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27040053 | 1.00 | IRAK4 (0.67) | IRAK4 | |
| SCHEMBL31664169 | 0.96 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL21070032 | 0.96 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL30726378 | 0.96 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL30726379 | 0.96 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL30726293 | 0.90 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL27039560 | 0.90 | IRAK4 (0.69) | IRAK4 | |
| SCHEMBL23806213 | 0.87 | IRAK4 (0.73) | IRAK4 | |
| SCHEMBL30726296 | 0.86 | IRAK4 (0.65) | IRAK4 | |
| SCHEMBL27039602 | 0.86 | IRAK4 (0.65) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558495-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | Bristol-Myers Squibb Company (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020084-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-25 | — | — | WO | disclosed |