SCHEMBL30726552

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C

nearest known ligand 0.65

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	11/20	0.65

▸	GLP1R	P43220	5/20	0.62

▸	ECE1	P42892	1/20	0.62

▸	MUS81	Q96NY9	1/20	0.62

▸	NR3C1	P04150	3/20	0.62

▸	GCGR	P47871	1/20	0.59

▸	GIPR	P48546	1/20	0.59

▸	GRPR	P30550	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31000950	0.97	IL23R (0.69)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL31000880	0.94	IL23R (0.68)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL30906573	0.90	IL23R (0.68)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL30906562	0.90	IL23R (0.68)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL30658330	0.90	GLP1R (0.70)	GLP1RECE1MUS81
SCHEMBL29479897	0.90	IL23R (0.65)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL30906537	0.89	IL23R (0.69)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL30712918	0.89	PRMT1 (0.61)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL30906474	0.89	GLP1R (0.67)	IL23RGLP1RECE1MUS81NR3C1
SCHEMBL29676608	0.89	GLP1R (0.64)	IL23RGLP1RECE1MUS81NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024020063-A2	ANTI-HRF ANTIBODIES	LA JOLLA INSTITUTE FOR IMMUNOLOGY (US)	2024-01-25	—	—	WO	disclosed