SCHEMBL30726570

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)CN)[C@@H](C)O)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	10/20	0.62

▸	NPY4R	P50391	8/20	0.62

▸	NPY5R	Q15761	8/20	0.62

▸	NPY1R	P25929	8/20	0.62

▸	MAPK8	P45983	1/20	0.55

▸	MAPK9	P45984	1/20	0.55

▸	MAPK10	P53779	1/20	0.55

▸	TFPI	P10646	2/20	0.55

▸	EPHA2	P29317	2/20	0.54

▸	GLP1R	P43220	1/20	0.53

▸	CALCR	P30988	2/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906392	0.92	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30906560	0.92	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL31000897	0.91	NPY2R (0.58)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30975049	0.90	CALCR (0.65)	NPY2RNPY4RNPY5RNPY1RGLP1R
SCHEMBL30824282	0.90	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL31182572	0.89	NPY2R (0.62)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30495779	0.88	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL31182683	0.87	NPY2R (0.71)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL31182858	0.87	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30906377	0.87	NPY2R (0.71)	NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024020063-A2	ANTI-HRF ANTIBODIES	LA JOLLA INSTITUTE FOR IMMUNOLOGY (US)	2024-01-25	—	—	WO	disclosed