SCHEMBL30726576

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)O)[C@@H](C)CC)[C@@H](C)CC)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	14/20	0.69

▸	ECE1	P42892	1/20	0.64

▸	MUS81	Q96NY9	1/20	0.64

▸	RXFP1	Q9HBX9	1/20	0.62

▸	CCKBR	P32239	1/20	0.61

▸	PTH1R	Q03431	4/20	0.61

▸	NPY1R	P25929	1/20	0.61

▸	NPY2R	P49146	1/20	0.61

▸	NPY4R	P50391	1/20	0.61

▸	NPY5R	Q15761	1/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29479845	0.94	GLP1R (0.69)	GLP1RECE1MUS81RXFP1CCKBR
SCHEMBL31000894	0.93	GLP1R (0.69)	GLP1RECE1MUS81CCKBRNPY1R
SCHEMBL29649219	0.93	GLP1R (0.63)	GLP1RECE1MUS81RXFP1PTH1R
SCHEMBL31547376	0.92	GLP1R (0.70)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL31402804	0.91	GLP1R (0.71)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL30906359	0.91	GLP1R (0.63)	GLP1RECE1MUS81RXFP1NPY1R
SCHEMBL31000884	0.91	NPY2R (0.75)	GLP1RNPY1RNPY2RNPY4RNPY5R
SCHEMBL30906543	0.90	GLP1R (0.64)	GLP1RECE1MUS81CCKBRNPY1R
SCHEMBL30906394	0.90	GLP1R (0.64)	GLP1RECE1MUS81CCKBRNPY1R
SCHEMBL30906370	0.89	GLP1R (0.62)	GLP1RCCKBRPTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024020063-A2	ANTI-HRF ANTIBODIES	LA JOLLA INSTITUTE FOR IMMUNOLOGY (US)	2024-01-25	—	—	WO	disclosed