Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30727482 | 1.00 | PDE5A (0.75) | PDE5A | |
| SCHEMBL1679799 | 1.00 | PDE5A (0.75) | PDE5A | |
| SCHEMBL1679795 | 1.00 | PDE5A (0.75) | PDE5A | |
| SCHEMBL30435700 | 1.00 | PDE5A (0.75) | PDE5A | |
| SCHEMBL31143600 | 1.00 | PDE5A (0.75) | PDE5A | |
| SCHEMBL14283383 | 0.92 | PDE5A (0.69) | PDE5A | |
| SCHEMBL28912195 | 0.92 | PDE5A (0.72) | PDE5A | |
| SCHEMBL28417919 | 0.91 | PDE5A (0.71) | PDE5A | |
| SCHEMBL28417910 | 0.91 | PDE5A (0.71) | PDE5A | |
| SCHEMBL17283017 | 0.91 | PDE5A (0.62) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430591-A | Synthesis method of avanafil | 康普药业股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117430591-A | Synthesis method of avanafil | 康普药业股份有限公司 | 2024-01-23 | — | — | CN | disclosed |