Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387849 | 0.87 | KLK7 (0.54) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL17946769 | 0.86 | KLK7 (0.56) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL31011377 | 0.86 | KLK7 (0.54) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL29370367 | 0.86 | KLK7 (0.56) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL14064950 | 0.86 | KLK7 (0.54) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL2289677 | 0.86 | KLK7 (0.54) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL29628218 | 0.86 | KLK7 (0.56) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL2289683 | 0.86 | KLK7 (0.54) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL30631751 | 0.86 | KLK7 (0.54) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL20529968 | 0.85 | KLK7 (0.53) | KLK7KLK5MAPTTLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117563022-A | Trifunctional constructs with tunable pharmacokinetics for imaging and anti-tumor therapy | 康奈尔大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-110612126-B | Trifunctional constructs with tunable pharmacokinetics for imaging and anti-tumor therapy | 康奈尔大学 | 2023-11-03 | — | — | CN | disclosed |