Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 7/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30727724 | 0.80 | ABL1 (0.38) | PDE10APDE3BPDE3ANAMPTPIK3CD | |
| SCHEMBL30727657 | 0.78 | NAMPT (0.35) | NAMPTPIK3CDPIK3CA | |
| SCHEMBL30727670 | 0.78 | PDE10A (0.34) | PDE10APDE3BPDE3ASIGMAR1PIK3CD | |
| SCHEMBL30727610 | 0.77 | MAPT (0.36) | SIGMAR1NAMPT | |
| SCHEMBL30727682 | 0.77 | PIK3CD (0.39) | PDE10APDE3BPDE3ASIGMAR1PIK3CD | |
| SCHEMBL30727733 | 0.77 | PDE10A (0.37) | PDE10APDE3BPDE3ASIGMAR1TLR9 | |
| Hydrochloric Acid SCHEMBL30727642 | 0.77 | MAPT (0.35) | SIGMAR1NAMPT | |
| SCHEMBL30727750 | 0.77 | PDE10A (0.47) | PDE10APDE3BPDE3A | |
| SCHEMBL30727738 | 0.74 | PIK3CA (0.35) | NAMPTPIK3CDPIK3CA | |
| SCHEMBL30727639 | 0.74 | PIK3CA (0.35) | NAMPTPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532495-A1 | CD73 INHIBITOR COMPOUNDS | Adorx therapeutics Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-119585273-A | CD73 inhibitor compounds | 阿道尔克斯治疗有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2023233130-A1 | CD73 INHIBITOR COMPOUNDS | AdoRx Therapeutics Limited (GB) | 2023-12-07 | — | — | WO | disclosed |