Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.45 |
| ▸ | CBL | P22681 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27068035 | 1.00 | CBLB (0.45) | CBLBCBL | |
| SCHEMBL32667109 | 0.97 | CBLB (0.46) | CBLBCBL | |
| SCHEMBL27068042 | 0.97 | CBLB (0.46) | CBLBCBL | |
| SCHEMBL27068167 | 0.89 | BRD4 (0.40) | CBLBCBL | |
| SCHEMBL27068001 | 0.87 | CBLB (0.45) | CBLBCBL | |
| SCHEMBL27068000 | 0.86 | CBLB (0.54) | CBLBCBL | |
| SCHEMBL27041326 | 0.84 | CBLB (0.52) | CBLBCBL | |
| SCHEMBL31319139 | 0.84 | CBLB (0.46) | CBLBCBL | |
| SCHEMBL27068004 | 0.84 | CBLB (0.46) | CBLBCBL | |
| SCHEMBL32666907 | 0.84 | CBLB (0.47) | CBLBCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558501-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |