Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1794781 | 0.88 | TRPV1 (0.42) | ALOX5APFEN1TRPV1 | |
| SCHEMBL1798733 | 0.82 | TRPV1 (0.45) | ALOX5APFEN1TRPV1 | |
| SCHEMBL1794423 | 0.82 | ALOX5AP (0.38) | ALOX5APFEN1TRPV1 | |
| SCHEMBL1798102 | 0.81 | TRPV1 (0.39) | ALOX5APFEN1TRPV1 | |
| SCHEMBL12350216 | 0.81 | TRPV1 (0.42) | ALOX5APFEN1TRPV1 | |
| SCHEMBL1799525 | 0.80 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL1795829 | 0.80 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL1801367 | 0.77 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL1797862 | 0.76 | TRPV1 (0.44) | ALOX5APFEN1TRPV1 | |
| SCHEMBL12350213 | 0.76 | TRPV1 (0.45) | ALOX5APFEN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021330-B1 | BENZIMIDAZOLE MODULATORS OF VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-22 | — | — | EP | claimed |