Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728803 | 1.00 | PRMT1 (0.50) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL27042490 | 1.00 | PRMT1 (0.50) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL30728789 | 0.93 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL31533989 | 0.93 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL30728753 | 0.93 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL30728743 | 0.87 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL30728797 | 0.87 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL31533979 | 0.87 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL27042482 | 0.87 | PRMT1 (0.49) | PRMT1LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL4484948 | 0.83 | TSHR (0.46) | PRMT1LMNAMAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558489-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | disclosed |
| CN-119585248-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |