SCHEMBL30729445

SCHEMBL30729445

NCCCn1ccc2cc(Br)ccc21

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56
HTR7 P34969 7/20 0.51
PLG P00747 1/20 0.49
PLAU P00749 1/20 0.49
CDK4 P11802 4/20 0.44
CCND1 P24385 4/20 0.44
NTSR1 P30989 1/20 0.40
ROCK1 Q13464 1/20 0.39
CYP3A4 P08684 1/20 0.39
KRAS P01116 1/20 0.38
HTR6 P50406 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21941497 0.90 HTR2A (0.59) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL4939152 0.83 HTR2A (0.56) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL18941301 0.83 HTR2A (0.53) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL30388499 0.82 HTR2A (0.51) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL18856950 0.82 HTR2A (0.55) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL28993624 0.82 HTR2A (0.51) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL22930065 0.81 HTR2A (0.54) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL15550237 0.81 HTR2A (0.54) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL28550149 0.81 HTR2A (0.54) HTR2AHTR2CHTR7PLGPLAU
SCHEMBL22930053 0.80 HTR2A (0.60) HTR2AHTR2CHTR7PLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285528-A Five membered heterocyclic indole derivatives 南开大学 2023-12-26 CN disclosed