SCHEMBL30729466

CC(C)C[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	NPY1R	P25929	1/20	0.59

▸	NPY2R	P49146	1/20	0.59

▸	NPY4R	P50391	1/20	0.59

▸	KISS1R	Q969F8	7/20	0.59

▸	BACE1	P56817	5/20	0.55

▸	OPRL1	P41146	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29598823	0.89	NPY1R (0.58)	NPY1RNPY2RNPY4RKISS1ROPRL1
SCHEMBL29599378	0.88	NPY1R (0.56)	NPY1RNPY2RNPY4RKISS1ROPRL1
SCHEMBL27076913	0.87	NPY1R (0.69)	NPY1RNPY2RNPY4RKISS1RBACE1
SCHEMBL29359131	0.87	NPY1R (0.69)	NPY1RNPY2RNPY4RKISS1RBACE1
SCHEMBL30799652	0.86	BACE1 (0.67)	BACE1
SCHEMBL30130346	0.85	BACE1 (0.57)	BACE1
SCHEMBL31484077	0.85	BACE1 (0.58)	BACE1
SCHEMBL31396396	0.85	NPY1R (0.68)	NPY1RNPY2RNPY4RBACE1
SCHEMBL30799664	0.84	PTPN1 (0.61)	BACE1
SCHEMBL30799892	0.84	BACE1 (0.69)	BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240417437-A1	Linker Polypeptides	Trutino Biosciences Inc. (US)	2024-12-19	—	—	US	disclosed
US-20240043489-A1	Cytokine Prodrugs Comprising a Cleavable Linker	Trutino Biosciences Inc. (US)	2024-02-08	—	—	US	disclosed