Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178429 | 0.85 | MAPT (0.71) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL28589171 | 0.82 | MEN1 (0.57) | MAPTALDH1A1LMNAHTTNPC1 | |
| SCHEMBL28575872 | 0.82 | MEN1 (0.57) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL12997450 | 0.82 | MAPT (0.67) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL20150736 | 0.82 | MAPT (0.67) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL28575869 | 0.82 | MEN1 (0.57) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL10975281 | 0.82 | MAPT (0.67) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL28589184 | 0.82 | MEN1 (0.57) | MAPTTDP1POLBALDH1A1LMNA | |
| SCHEMBL28581175 | 0.82 | MEN1 (0.57) | MAPTALDH1A1LMNAHTTNPC1 | |
| SCHEMBL26502909 | 0.82 | MAPT (1.00) | MAPTTDP1POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623968-A | Method for preparing N-substituted lactamide by catalyzing polylactic acid aminolysis with ionic liquid | 中国科学院化学研究所 | 2024-03-01 | — | — | CN | disclosed |