Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.70 |
| ▸ | BRAF | P15056 | 14/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541508 | 1.00 | KDR (0.70) | KDRBRAF | |
| SCHEMBL30729916 | 1.00 | KDR (0.70) | KDRBRAF | |
| SCHEMBL27311398 | 0.96 | KDR (0.66) | KDRBRAF | |
| SCHEMBL27305737 | 0.86 | KDR (0.54) | KDRBRAF | |
| SCHEMBL18099204 | 0.86 | KDR (0.69) | KDRBRAF | |
| SCHEMBL15559536 | 0.85 | KDR (0.69) | KDRBRAF | |
| SCHEMBL16895204 | 0.84 | KDR (0.64) | KDRBRAF | |
| SCHEMBL29834742 | 0.84 | KDR (0.51) | KDRBRAF | |
| SCHEMBL16907661 | 0.83 | KDR (1.00) | KDRBRAF | |
| SCHEMBL16895218 | 0.82 | MAPK14 (0.53) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |