Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279612 | 1.00 | HRH3 (0.44) | HRH3SIRT2GPR119TDP2PARP10 | |
| SCHEMBL29279610 | 0.89 | PPARG (0.37) | HRH3SIRT2GPR119TDP2PTGS2 | |
| SCHEMBL28590447 | 0.89 | CA12 (0.34) | HRH3SIRT2MEN1KMT2AMAPT | |
| SCHEMBL29629328 | 0.89 | CA12 (0.34) | HRH3SIRT2MEN1KMT2AMAPT | |
| SCHEMBL28590451 | 0.89 | CA12 (0.34) | HRH3SIRT2MEN1KMT2AMAPT | |
| SCHEMBL30731534 | 0.89 | PPARG (0.37) | HRH3SIRT2GPR119TDP2PTGS2 | |
| SCHEMBL28586495 | 0.88 | PARP10 (0.40) | HRH3SIRT2PARP10PARP11MAPT | |
| SCHEMBL29629333 | 0.88 | PARP10 (0.40) | HRH3SIRT2PARP10PARP11MAPT | |
| SCHEMBL28586497 | 0.88 | PARP10 (0.40) | HRH3SIRT2PARP10PARP11MAPT | |
| SCHEMBL29629338 | 0.85 | HDAC4 (0.39) | HRH3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-B | Method for preparing 3-substituted chromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-03-05 | — | — | CN | disclosed |